Name;(D-Lys³)-GHRP-6
Synonyms;(D-Trp7,D-Lys8,(D-Lys3)-Growth Hormone-Releasing Peptide-6,D-Phe10)-a-MSH (6-11) amide
CAS ;136054-22-3
MDL ;MFCD00214665
Sequence;H-His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH₂
Molecular Weight;930.12
Molecular Formula;C₄₉H₆₃N₁₃O₆
Storage Conditions;–20 ± 5 °C
Description:
A ghrelin receptor antagonist. Asakawa et al. found that peripherally administered (D-Lys3)-GHRP-6 (HwkWfK-amide) decreased food intake in lean mice, in mice with diet induced obesity, and in ob/ob obese mice, and that repeated administration of this GHS-R antagonist decreased body weight gain and improved glycaemic control in ob/ob obese mice.
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